NURS FPX 8030 Assessment 2 Evidenced-Based Literature Search and Organization
NURS FPX 8030 Assessment 2 Evidenced-Based Literature Search and Organization Name Capella university NURS-FPX 8030 Evidence-Based Practice Process for the Nursing Doctoral Learner Prof. Name Date Patient Safety Issue, PICO(T) Question and Evidence Hospital Acquired Infections (HAIs) pose a threat to patients’ safety at the Memorial Regional Hospital especially in Intensive Care Units (ICUs). The incidence rates Central Line-Associated Bloodstream Infections (CLABSI), Catheter-Associated Urinary Tract Infections (CAUTI) and other HAIs have been on the rise, resulting in higher mortality, morbidities and increased health care costs. Internal data from Memorial Regional Hospital reveals CLABSI and CAUTI rates of 0.553 and 0.926 per 1,000 device days, respectively, in 2023, which exceed national benchmarks (Leapfrog, 2024). The HAIs compromise patient safety, prolong recovery, and strain hospital resources, necessitating immediate intervention to reduce their incidence. Gaps in infection control practices, identified through staff interviews and internal data, contribute to the prevalence of HAIs in ICUs. External evidence supports the urgency for change. Peters et al. (2022) highlight the importance of hand hygiene, environmental cleanliness, antimicrobial stewardship, and staff education in preventing HAIs. CDC (2024) reports that one in 31 hospitalized patients acquire an HAI annually, resulting in over 72,000 deaths. The findings stress the need for multifaceted, evidence-based strategies to reduce HAIs and improve patient safety at Memorial Regional Hospital. The PICOT Question In ICU patients at Memorial Regional Hospital (P), how does the implementation of hand hygiene protocol (I), as compared to current practices (C), affect the rate of HAIs (O) over 12 weeks (T)? Best Evidence Search Strategy Establishing an efficient approach to developing the search terms is crucial to finding the most relevant evidence for the PICOT question about Memorial Regional Hospital and ICU patients and the impact of a comprehensive hand hygiene protocol on the rates of HAIs. In identifying the main components of the PICOT question, ICU patients are the population of interest, and a hand hygiene protocol and antimicrobial stewardship are the interventions of choice compared to the current practice in reducing HAIs and enhancing patient safety (Akkoc et al., 2021). PubMed, CINAHL, and the Cochrane Library databases were used, since these are rich sources of medical, nursing, and clinical research articles (Kuti et al., 2021). Such an approach guarantees access to the most relevant evidence for implementing such interventions in the ICU. The PRISMA flowchart is presented in the Appendix to outline the process of study identification and inclusion and exclusion criteria. Databases and Keywords Selecting appropriate databases and keywords is critical for conducting an effective search to gather the best evidence on the impact of a hand hygiene protocol and antimicrobial stewardship on HAIs in ICU patients. Databases such as PubMed, CINAHL, and the Cochrane Library were utilized for their extensive collections of high-quality clinical and nursing research (Kuti et al., 2021). Key search terms included “hand hygiene,” “Healthcare-Associated Infections (HAIs),” and “infection prevention.” Boolean operators like AND, OR, and NOT optimized the search by refining and expanding it to identify relevant studies that could guide quality improvement initiatives. Inclusion and Exclusion Criteria The selection criteria involved articles in English published after 2019 that compared the effects of hand hygiene and antimicrobial stewardship on HAIs in ICU patient populations. The inclusion criteria included studies with samples of ICU patients, reported at least one of the PICOT question’s outcomes, such as CLABSI and CAUTI rates, and contained evidence-based interventions. Studies performed outside the ICU were excluded, and studies with pediatric patients and those addressing other types of interventions other than hand hygiene were excluded (Raoofi et al., 2023). According to these criteria and to ensure the quality of the articles selected, the authors screened and included 12 articles in the review. Only articles directly relevant to the issue were included in the review, thus proving the effectiveness of targeted interventions in decreasing HAIs and increasing patient safety (Raoofi et al., 2023). A total of 12 studies were retained as they provided information on the applicability of interventions in ICUs, which closely matched addressing HAIs at Memorial Regional Hospital. References Akkoc, G., Soysal, A., Gul, F., Kepenekli Kadayifci, E., Arslantas, M. K., Yakut, N., Bilgili, B., Ocal Demir, S., Haliloglu, M., Kasapoglu, U., & Cinel, I. (2021). Reduction of nosocomial infections in the intensive care unit using an electronic hand hygiene compliance monitoring system. The Journal of Infection in Developing Countries, 15(12), 1923–1928. https://doi.org/10.3855/jidc.14156 CDC. (2024). HAIs: Reports and data. Centers for Disease Prevention and Control.gov. https://www.cdc.gov/healthcare-associated-infections/php/data/?CDC_AAref_Val=https://www.cdc.gov/hai/data/portal/index.html Kuti, B. P., Ogunlesi, T. A., Oduwole, O., Oringanje, C., Udoh, E. E., & Meremikwu, M. M. (2021). Hand hygiene for the prevention of infections in neonates. Cochrane Database of Systematic Reviews, 21(7). https://doi.org/10.1002/14651858.cd013326.pub3 NURS FPX 8030 Assessment 2 Evidenced-Based Literature Search and Organization Leapfrog. (2024). Hospital details table. Hospitalsafetygrade.org. https://www.hospitalsafetygrade.org/table-details/memorial-regional-hospital Peters, A., Schmid, M. N., Parneix, P., Lebowitz, D., de Kraker, M., Sauser, J., Zingg, W., & Pittet, D. (2022). Impact of environmental hygiene interventions on healthcare-associated infections and patient colonization: A systematic review. Antimicrobial Resistance & Infection Control, 11(1), 1–9. https://doi.org/10.1186/s13756-022-01075-1 Raoofi, S., Pashazadeh Kan, F., Rafiei, S., Hosseinipalangi, Z., Noorani Mejareh, Z., Khani, S., Abdollahi, B., Seyghalani Talab, F., Sanaei, M., Zarabi, F., Dolati, Y., Ahmadi, N., Raoofi, N., Sarhadi, Y., Masoumi, M., sadat Hosseini, B., Vali, N., Gholamali, N., Asadi, S., & Ahmadi, S. (2023). Global prevalence of nosocomial infection: A systematic review and meta-analysis. Public Library of Science, 18(1), e0274248. https://doi.org/10.1371/journal.pone.0274248 Appendix Identification of Studies Via Databases and Registers Search Strategy Selecting Databases: The search was done by using PubMed, CINAHL, and the Cochrane Library databases. These databases were selected based on their ability to provide coverage of biomedical and nursing literature, providing the best information on hand hygiene standards and HAI prevention in the ICU. Initial Search Results: A total of 25 records were identified across the selected databases. No additional records were found in registers or other sources. Screening Process: The first 25 records were excluded by reviewing the title and abstract of each record in order to evaluate relevance to the PICOT question. A total of 9 records were excluded after the screening due to irrelevance or poor quality. Eligibility Criteria: